You may experience side effects from JEMPERLI

JEMPERLI is a medicine that may treat certain cancers by working with your immune system. JEMPERLI can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. These problems may happen anytime during treatment or even after your treatment has ended.

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10% of patients stopped taking JEMPERLI completely and 28% of patients had their treatment interrupted due to side effects

Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:

  • Lung problems.

    • cough
    • shortness of breath
    • chest pain
  • Intestinal problems.

    • diarrhea or more bowel movements than usual
    • stools that are black, tarry, sticky, or have blood or mucus
    • severe stomach-area (abdomen) pain or tenderness
  • Liver problems.

    • yellowing of your skin or the whites of your eyes
    • severe nausea or vomiting
    • pain on the right side of your stomach area (abdomen)
    • dark urine (tea colored)
    • bleeding or bruising more easily than usual
  • Hormone gland problems.

    • headaches that will not go away or unusual headaches
    • eye sensitivity to light
    • eye problems
    • rapid heartbeat
    • increased sweating
    • extreme tiredness
    • weight gain or weight loss
    • feeling more hungry or thirsty than usual
    • urinating more often than usual
    • hair loss
    • feeling cold
    • constipation
    • your voice gets deeper
    • dizziness or fainting
    • changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness
  • Kidney problems.

    • change in the amount or color of your urine
    • blood in your urine
    • swelling in your ankles
    • loss of appetite
  • Skin problems.

    • rash
    • itching
    • skin blistering or peeling
    • painful sores or ulcers in your mouth or in your nose, throat, or genital area
    • fever or flu-like symptoms
    • swollen lymph nodes
  • Problems in other organs and tissues.

    These are not all of the signs and symptoms of immune system problems that can happen with JEMPERLI. Call or see your healthcare provider right away for any new or worse signs or symptoms.

    • chest pain, irregular heartbeat, shortness of breath, swelling of ankles
    • confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems, tingling or numbness of the arms or legs
    • double vision, blurry vision, sensitivity to light, eye pain, changes in eyesight
    • persistent or severe muscle pain or weakness, muscle cramps
    • low red blood cells, bruising
  • Infusion reactions that can sometimes be severe or life-threatening.

    • chills or shaking
    • itching or rash
    • flushing
    • shortness of breath or wheezing
    • dizziness
    • feel like passing out
    • fever
    • back or neck pain
  • Rejection of a transplanted organ.

    • Your healthcare provider should tell you what signs and symptoms you should report and monitor you, depending on the type of organ transplant that you have had.
  • Complications, including graft-versus-host-disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic).

    • These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with JEMPERLI. Your healthcare provider will monitor you for these complications.

Getting medical treatment right away may help keep these problems from becoming more serious.

Your healthcare provider will check you for these problems during treatment with JEMPERLI. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with JEMPERLI if you have severe side effects.

The most common side effects of JEMPERLI include tiredness and weakness, low red blood cell count (anemia), diarrhea, nausea, decreased number of certain white blood cells, decreased albumin in the blood, increase in certain liver blood tests, and decreased salt (sodium) in the blood.

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How may JEMPERLI fight cancer?

See How JEMPERLI Works

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How may JEMPERLI help?

See the Benefits of JEMPERLI